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Cyclo (CRLLIF)

CAT: 0931-TP3513-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3513-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism, Chromatin/Epigenetic
Bioactivity
Cyclo CRLLIF serves as a dual inhibitor of hypoxia-inducible factors HIF1 and HIF2, disrupting the interaction between HIF1-α and HIF2-α with HIF1-β. It exhibits dissociation constants (KD) of 14.5 μM for HIF1-α and 10.2 μM for HIF2-α within the PAS-B domains.
Molecular Formula
C36H59N9O6S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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