Cyclo (-RGDfK)

• Target:

  Integrin

• Related Pathways:

  Cytoskeletal Signaling

• Purity:

  >99.99%

• Bioactivity:

  Cyclo (-RGDfK) is a potent and selective inhibitor of integrin ?v?3 with IC50 of 0.94 nM. Cyclo specifically targets tumor microvasculature and cancer cells by binding to ?v?3 integrin on the cell surface.

• Smiles:

  NCCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

• Molecular Formula:

  C27H41N9O7

• Molecular Weight:

  603.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  161552-03-0