AMG-424

CAT: 0931-T9901A-1062-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T9901A-1062-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CD38
Related Pathways
Immunology/Inflammation
Bioactivity
AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 and CD3E. It effectively kills cancer cells that express CD38, stimulates T cell proliferation, and reduces cytokine release. AMG-424 exhibits antitumor activity in mouse cancer models with bone marrow invasion and induces peripheral B cell depletion in cynomolgus monkeys. It is used in studies of multiple myeloma. Recommended isotype control: half-IG G1-kappa/ (scFv-heavy-lambda) -h-CH2-CH3.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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