JYQ-164

• Target:

  PTEN

• Related Pathways:

  PI3K/Akt/mTOR signaling

• Bioactivity:

  JYQ-164 is a small molecule inhibitor targeting human Parkinson's disease protein 7 (PARK7/DJ-1) . It functions by covalently and selectively targeting the critical residue Cys106 of PARK7, exhibiting an IC50 of 21 nM. JYQ-164 demonstrates five times greater inhibitory potency against PARK7 compared to the previously reported inhibitor, JYQ-88. It is applicable for research in Parkinson's disease and cancer.

• Molecular Formula:

  C23H26N6O5S2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C