TX-2552

CAT: 0931-T89234-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T89234-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2446767-14-0

Bioactivity

TX-2552 is an orally effective inhibitor of tyrosyl-DNA phosphodiesterase 1 (TDP1), with an IC50 value of 0.62 μM. It enhances the cleavage activity of topotecan in mouse bone marrow cells and amplifies the antitumor effects of topotecan in Krebs-2 ascites tumor-bearing mice.

Smiles

O=C1C=C(C=2C(=CC(OC/C=C(/CCC=C(C)C)\C)=CC2)O1)C3=CC=C(F)C=C3

Molecular Formula

C25H25FO3

Molecular Weight

392.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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TX-2552

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