IV-255

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain, which heightens DNA damage when administered with Temozolomide and Bleomycin, curtails the invasiveness of GBM cells, and augments both Temozolomide-induced cell death and Temozolomide's apoptosis-inducing activity [1].

• Molecular Formula:

  C19H19F2N3O2

• Molecular Weight:

  359.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C