TX-1123

• Target :

  Others|||Src|||PKA|||PKC|||EGFR|||COX|||CaMK

• Related Pathways :

  Angiogenesis|||Others|||Neuroscience|||Immunology/Inflammation|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Bioactivity :

  TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 ?M for COX2 and 15.7 ?M for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.

• Smiles :

  C(C)(C)(C)C1=C(O)C(C(C)(C)C)=CC(C=C2C(=O)C=CC2=O)=C1

• Molecular Formula :

  C20H24O3

• Molecular Weight :

  312.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  157397-06-3