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TX-1123

CAT: 931-T70431-01Size: 25 mgDry Ice: NoHazardous: No
25 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
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CAS Number
157397-06-3
Target
Others|||Src|||PKA|||PKC|||EGFR|||COX|||CaMK
Related Pathways
Angiogenesis|||Others|||Neuroscience|||Immunology/Inflammation|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Bioactivity
TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 ?M for COX2 and 15.7 ?M for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.
Smiles
C(C)(C)(C)C1=C(O)C(C(C)(C)C)=CC(C=C2C(=O)C=CC2=O)=C1
Molecular Formula
C20H24O3
Molecular Weight
312.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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