SCAL-255

CAT: 0931-T79476-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T79476-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2798953-61-2

Target

OXPHOS, Mitochondrial Metabolism

Related Pathways

Apoptosis, Metabolism

Bioactivity

SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM. It impedes mitochondrial function by blocking oxygen consumption rate (OCR), inducing reactive oxygen species (ROS) production, and diminishing mitochondrial membrane potential (MMP) . Furthermore, SCAL-255 significantly hampers the proliferation of cancer cells reliant on oxidative phosphorylation (OXPHOS) [1].

Smiles

C(C=1C=C(N2CCN(C(=O)C3CC3)CC2)C=CC1)N4N=C(C(NC5=CC=C(OC(F)(F)F)C=C5)=O)C=C4C

Molecular Formula

C27H28F3N5O3

Molecular Weight

527.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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SCAL-255

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