Products for Research Use Only

PBA-AMF

CAT: 0931-T89007-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89007-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
PBA-AMF is activated by H2O2, releasing formamide (AMF) . This compound selectively inhibits the proliferation of breast cancer cells without affecting non-cancerous cells. It works by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis (Apoptosis), and arresting the cell cycle, thereby suppressing tumor growth. PBA-AMF is useful in studies of tumors and other diseases associated with elevated levels of H2O2.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C