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PBE-AMF

CAT: 0931-T88991-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T88991-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Reactive Oxygen Species|||Apoptosis|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||NF-?B|||Immunology/Inflammation|||Apoptosis|||Metabolism|||Cell Cycle/Checkpoint
Bioactivity
PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 ?M) while sparing non-cancerous MCF-10A cells.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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