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PBE-AMF

CAT: 0931-T88991-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88991-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Reactive Oxygen Species, Apoptosis, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, NF-κB, Immunology/Inflammation, Apoptosis, Metabolism, Cell Cycle/Checkpoint
Bioactivity
PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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