PBA-1105b

• Target:

  P62|||AUTACs|||Autophagy

• Related Pathways:

  PROTAC|||Autophagy

• Bioactivity:

  PBA-1105b, a longer PEGylated derivative of PBA-1105, is an autophagy-targeting chimeric compound (AUTOTAC) that can induce self-oligomerization of p62. It enhances the autophagic flux of Ub-bound aggregates.

• Smiles:

  O=C(NCCOCCOCCOCCOCCOCCOCCOCCNCC1=CC=C(OCC=2C=CC=CC2)C(OCC=3C=CC=CC3)=C1)CCCC=4C=CC=CC4

• Molecular Formula:

  C47H64N2O10

• Molecular Weight:

  817.02

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2941386-60-1