Products for Research Use Only

TPP-1 TFA

CAT: 0931-T76198-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76198-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PD-1/PD-L1
Related Pathways
Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint
Bioactivity
TPP-1 TFA, a potent inhibitor of the PD-1/PD-L1 interaction, selectively binds to PD-L1 with high affinity (K D =95 nM) . It effectively inhibits human tumor growth in vivo by reactivating T-cell function [1].
Molecular Formula
C109H151F3N34O34S2
Molecular Weight
2602.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C