TPP-IOA

CAT: 0931-T212163-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T212163-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1423018-61-4
Target
Apoptosis|||OXPHOS|||Mitochondrial Metabolism
Related Pathways
Metabolism|||Apoptosis
Bioactivity
TPP-IOA is a cytochrome c peroxidase inhibitor. It prevents apoptosis by blocking cardiolipin oxidation and the release of cytochrome c into the cytosol. TPP-IOA interferes with oxidative phosphorylation in isolated mitochondria. It inhibits cell death of SH-SY5Y cells in glucose medium but is ineffective in galactose medium. Additionally, TPP-IOA induces mitochondrial depolarization and network fragmentation, and it reduces radiation-induced mortality in mice.
Smiles
[P+](CCCOC(CCCCCCC/C=C\C[C@H](CCCCCC)N1C=CN=C1)=O)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
Molecular Formula
C42H56BrN2O2P
Molecular Weight
731.78
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T201626-01TPP-resveratrol
T87996-01TPP-Ce6
TP2850-01Tpp-CAQK
T211518-01CPPA-TPP
T74363-01Chol-TPP
T76197-01TPP-1
T11355Gamitrinib TPP
T76198-01TPP-1 TFA
T19662-01Decyl-TPP bromide
TYD-00676-01Cobalt (II) TPP

Alternative Products

CatalogName
HY-176775TPP-IOA
MBS387652-01Gamitrinib TPP
MBS3847412-01TPP-1
464507TPP-d4
23253991-100gTriphenylphosphine (TPP)
HY-159734-01TPP-resveratrol
MBS5816327Chol-TPP
HY-158189TPP-Ce6
bs-82711C-01Dodecyl-TPP
HY-P10707Tpp-CAQK

Popular Products