NHS-Modified MMAF

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  NHS-Modified MMAF (WO2012143499A2, intermediate 210) is an intermediate used for producing anti-mesothelin binder-agent conjugates (ADCs) [1].

• Smiles:

  C([C@@H](C(=O)N1CCCCO1)NC([C@@H]([C@@H](OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(CCCCCC(ON3C(=O)CCC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H])C)=O)C=4C=5C(NC4)=CC=CC5

• Molecular Formula:

  C55H86N8O12

• Molecular Weight:

  1051.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1404073-10-4