MMAF-OMe

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Purity:

  0.9934

• Bioactivity:

  MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. MMAF-Ome is also an ADC cytotoxin.

• Smiles:

  CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

• Molecular Formula:

  C40H67N5O8

• Molecular Weight:

  745.99

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  863971-12-4