NHS-Modified MMAF

• Description :

  NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) [1].

• UNSPSC :

  12352005

• Target :

  Drug-Linker Conjugates for ADC

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/nhs-modified-mmaf.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45

• Molecular Formula :

  C55H86N8O12

• Molecular Weight :

  1051.32

• References & Citations :

  [1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1404073-10-4]