NHS-Modified MMAF

• UNSPSC Description:

  NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs)[1].

• Target Antigen:

  Drug-Linker Conjugates for ADC

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/nhs-modified-mmaf.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45

• Molecular Weight:

  1051.32

• References & Citations:

  [1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1404073-10-4