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MMAF Hydrochloride

CAT: 0931-T16121-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T16121-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415246-68-2
Target
Microtubule Associated, ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
Bioactivity
MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.
Smiles
Cl.[H][C@](NC(=O)[C@@H](NC)C(C)C)(C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O)OC
Molecular Formula
C39H66ClN5O8
Molecular Weight
768.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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