NHS-Modified MMAF (TFA)

• Description:

  NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Purity:

  96.03

• Smiles:

  O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45.OC(C(F)(F)F)=O

• Molecular Formula:

  C57H87F3N8O14

• Molecular Weight:

  1165.34

• References & Citations:

  [1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported