NHS-Modified MMAF (TFA)

CAT: 0804-HY-139325A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-139325A-01Size:5 mg
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Description
NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) [1].
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Purity
96.03
Smiles
O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45.OC(C(F)(F)F)=O
Molecular Formula
C57H87F3N8O14
Molecular Weight
1165.34
References & Citations
[1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported

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