USP1-IN-7

• Target:

  DUB

• Related Pathways:

  Ubiquitination|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  USP1-IN-7 (Compound 3), a potent inhibitor of ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, exhibits an inhibition concentration (IC 50) of ?50 nM. It also effectively inhibits the proliferation of MDA-MB-436 cells at similar concentrations [1].

• Smiles:

  C(N1C=2C(N(C)C1=O)=CN=C(C2F)C=3C(=NC=NC3OC)C4CC4)C5=CC=C(C=C5)C6=NC(C(F)(F)F)=CN6C

• Molecular Formula:

  C27H23F4N7O2

• Molecular Weight:

  553.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033480-42-8