NMS-P953

• Target :

  Others|||JAK

• Related Pathways :

  Stem Cells|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Others|||JAK/STAT signaling|||Chromatin/Epigenetic

• Bioactivity :

  NMS-P953 is a JAK2 inhibitor, displaying significant tumor growth inhibition in SET-2 xenograft tumor model. NMS-P953 has a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile.

• Smiles :

  C(N)(=O)C1=C(NC(=C1)C2=NC(N)=NC=C2)C3=CC(C(F)(F)F)=CC=C3Cl

• Molecular Formula :

  C16H11ClF3N5O

• Molecular Weight :

  381.74

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1403679-33-3