JE-133

• CAS Number :

  2579171-69-8

• Target :

  Akt|||p38 MAPK|||PI3K

• Related Pathways :

  MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Bioactivity :

  JE-133, an optically active isochromane-2H-chromene conjugate, displays both antioxidant and anti-inflammatory properties. As a neuroprotective agent, it effectively counters neuronal oxidative damage through modulation of the PI3K/Akt and MAPK signaling pathways. Additionally, JE-133 can suppress lipopolysaccharide (LPS) -induced neuroinflammation by influencing the JAK/STAT and Nrf2 signaling pathways [1] [2].

• Smiles :

  C(OCC)(=O)[C@@H]1C(=CC=2C(O1)=CC=C(OC)C2)[C@H]3C=4C(C[C@@H](C)O3)=CC(O)=C(O)C4

• Molecular Formula :

  C23H24O7

• Molecular Weight :

  412.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C