KS-133

• Bioactivity:

  KS-133 is a selective and potent antagonist of the vasoactive intestinal peptide receptor 2 (VIPR2), exhibiting IC50 values of 24.8 nM in intracellular calcium influx assays and 500 nM in cAMP assays. This compound plays a crucial role in research on schizophrenia.

• Smiles:

  O=C1[C@]2 (N (C (=O) [C@@H] (NC (C) =O) CSSC[C@]3 (C (=O) N[C@H] (C (N[C@H] (C (N[C@@H] ([C@H] (CC) C) C (N) =O) =O) CC (C) C) =O) CC (=O) NCCCC[C@] (NC (=O) [C@]4 (N (C (=O) [C@H] (CC (C) C) NC (=O) [C@H] (CC5=CC=C (O) C=C5) NC (=O) [C@]6 (N1CCC6) [H]) CCC4) [H]) (C (=O) N[C@@H] (CC7=CC=C (O) C=C7) C (=O) N[C@@H] (CC (C) C) C (=O) N3) [H]) [H]) CCC2) [H]

• Molecular Formula:

  C75H111N15O17S2

• Molecular Weight:

  1558.9

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2724212-01-3