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HSD17B13-IN-14

CAT: 0931-T86604-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86604-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2758802-05-8
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-14 (Compound 4) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), achieving an IC 50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is utilized in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases like NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].
Smiles
C(NC(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C=C2)C=CS1)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C21H16ClN3O3S
Molecular Weight
425.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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