HSD17B13-IN-97

• UNSPSC Description:

  HSD17B13-IN-97 (compound 4) is a potent hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor with an IC50 value of ≤0.1 µM. HSD17B13-IN-97 has the potential for the research of Nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH) or or drug induced liver injury (DILI)[1].

• Target Antigen:

  17β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/hsd17b13-in-97.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(C(F)(F)F)N=C(C(NC2=CC=CC(N=CN3CC4=CC=CC=C4F)=C2C3=O)=O)C=C1

• Molecular Weight:

  458.37

• References & Citations:

  [1]Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. WO2022216626A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2849338-44-7