HSD17B13-IN-14
CAT:
804-HY-161215
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HSD17B13-IN-14
- CAS Number: 2758802-05-8
- UNSPSC Description: HSD17B13-IN-14 (Compound 4) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. HSD17B13-IN-14 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI)[1].
- Target Antigen: 17β-HSD
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/hsd17b13-in-14.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=C(NC(C2=CC=C(O)C(Cl)=C2)=O)C=CS1)NCC3=CNC4=C3C=CC=C4
- Molecular Weight: 425.89
- References & Citations: [1]Odingo J, et al. Thiophene hsd17b13 inhibitors and uses thereof. U.S., WO2022020714. 2023-09-07.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported