GNE-555

• Target :

  MTOR

• Related Pathways :

  PI3K/Akt/mTOR signaling

• Bioactivity :

  GNE-555, a selective and metabolically stable mTOR inhibitor (K i=1.5 nM), demonstrates good oral bioavailability and antiproliferative activity on PC3 and MCF-7 cells, making it suitable for cancer research [1] [2].

• Smiles :

  C[C@@H]1N(C2=C3C([C@@]4(N([C@](C3)(CC4)[H])C5COC5)[H])=NC(=N2)C6=CC=C(NC(NCC)=O)C=C6)CCOC1

• Molecular Formula :

  C26H34N6O3

• Molecular Weight :

  478.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1428902-71-9