ETC-168

• Target :

  MNK

• Related Pathways :

  MAPK

• Bioactivity :

  ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].

• Smiles :

  C(#N)C1=CC=C(C=2N3C(=NC2)C=CC(=N3)C4=CC=C(C(=O)N5CCOCC5)C=C4)C=C1

• Molecular Formula :

  C24H19N5O2

• Molecular Weight :

  409.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1464150-99-9