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Anticancer agent 168

CAT: 0931-T83082-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T83082-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
207399-56-2
Target
Others, Apoptosis, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Cell Cycle/Checkpoint, Others
Bioactivity
Compound D16 (Anticancer agent 168) is an inhibitor of DNA2 that induces apoptosis and cell-cycle arrest predominantly in the S-phase. It demonstrates anticancer efficacy and can counteract chemotherapy resistance in cancers harboring mutant p53 [1].
Smiles
CCN1C=C(C(O)=O)C(=O)C2=C1C=C(Cl)C(=C2)C1=CC=C(O1)[N+]([O-])=O
Molecular Formula
C16H11ClN2O6
Molecular Weight
362.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C