WJ-39

• Target:

  Mitophagy|||Reductase|||Apoptosis|||Mitochondrial Metabolism

• Related Pathways:

  Autophagy|||Endocrinology/Hormones|||Apoptosis|||Metabolism

• Purity:

  0.9945

• Bioactivity:

  WJ-39 is an orally active aldose reductase (AR) inhibitor that ameliorates renal lesions in diabetic nephropathy through activation of Nrf2 signaling, and may be used to ameliorate renal insufficiency and fibrosis.WJ-39 inhibits oxidative stress and inhibits the activation of the inflammatory vesicle of the oligomerization structural domain-like receptor family, pyrin structural domain 3 (NLRP3) .

• Smiles:

  O=C(CN1C=C(CC2=C(Cl)C(Cl)=CC=C2)C(C3=CC(OC)=CC=C31)=O)[O-].[K+]

• Molecular Formula:

  C19H14Cl2KNO4

• Molecular Weight:

  430.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3009908-95-3