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EGFR-IN-39

CAT: 0931-T63178-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63178-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2711105-48-3
Target
Others, EGFR
Related Pathways
JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-39, an acrylamide derivative, is a potent inhibitor of EGFR. EGFR-IN-39 is an antitumor agent with low toxicity and side effects. Among them, the overexpression and mutation of epidermal growth factor receptor (EGFR) have been clearly confirmed to cause uncontrollable cell growth, and are related to the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 has the potential to study EGFR mutation-related diseases.
Smiles
C(N)(=O)C=1N(N=C(C1N)C2CN(C(C=C)=O)CCC2)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3
Molecular Formula
C24H25ClN6O3
Molecular Weight
480.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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