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HAChE-IN-6

CAT: 0931-T82242-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82242-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, GSK-3, Cholinesterase (ChE)
Related Pathways
Stem Cells, Neuroscience, PI3K/Akt/mTOR signaling, Others
Bioactivity
HAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor with an IC50 of 0.16 μM. It also inhibits human butyrylcholinesterase (hBuChE) and glycogen synthase kinase 3 beta (GSK3β), with IC50 values of 0.69 μM and 0.26 μM, respectively. Additionally, hAChE-IN-6 impedes the self-aggregation of tau protein and amyloid-beta 1-42 (Aβ1-42), making it useful for Alzheimer's disease (AD) research [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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