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HAChE-IN-8

CAT: 0931-T209772-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209772-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
DYRK, Cholinesterase (ChE)
Related Pathways
Cell Cycle/Checkpoint, Neuroscience, Tyrosine Kinase/Adaptors
Bioactivity
HAChE-IN-8 (Compound S-12) is an orally active and selective inhibitor of hAChE, with an IC50 of 0.486 μM. It also inhibits BACE-1 with an IC50 of 0.542 μM, but shows negligible inhibition of Dyrk1A (IC50>10 μM) . This compound reduces Aβ aggregation, exhibits good blood-brain barrier penetration, and is primarily used in Alzheimer's disease research.
Molecular Formula
C25H22N4O4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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