Products for Research Use Only
RegisterLogin

PROTAC TTK degrader-1

CAT: 0931-T81375-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T81375-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2953426-43-0
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC TTK degrader-1, a potent threonine tyrosine kinase (TTK) PROTAC degrader, demonstrates DC50 values of 1.7 nM in COLO-205 cells and 5.8 nM in HCT-116 cells, indicating effective target degradation. Furthermore, it shows anticancer efficacy in a xenograft mouse model with COLO-205 human colorectal cancer cells [1].
Smiles
O=C1N(C=2C(=CN=C(NC3=C(OC)C=C(C=C3)N4CCN(C(CCCC#CC=5C=C6C(=CC5)C(=O)N(C6)C7C(=O)NC(=O)CC7)=O)CC4)N2)C(C)=C1)[C@H]8CC[C@@H](NC(CC)=O)CC8
Molecular Formula
C47H53N9O7
Molecular Weight
855.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T81374-01PROTAC TTK degrader-2
T74602-01PROTAC EZH2 Degrader-1
T18604PROTAC CRBN Degrader-1
T210284-01PROTAC JAK1 degrader 1
T210116-01PROTAC DYRK2 degrader 1
T209918-01PROTAC AKR1C3 degrader-1
T209844-01PROTAC TEAD degrader-1
T209626-01PROTAC Aster-A degrader-1
T209430-01PROTAC PAPD5 degrader 1
T208247-01PROTAC SMARCA2 degrader-1

Alternative Products

CatalogName
HY-178034PROTAC OSBP Degrader-1
HY-176857-01PROTAC STAT6 degrader-1
HY-175830PROTAC AURKA degrader 1
HY-175358PROTAC USP7 Degrader-1
HY-173135PROTAC KDM4 degrader-1
HY-172208-01PROTAC cGAS degrader-1
HY-163897-01PROTAC NCOA4 degrader-1
HY-163609PROTAC AKR1C3 degrader-1
HY-163938-01PROTAC erf3a Degrader-1
HY-162098PROTAC tubulin-Degrader-1

Popular Products