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Ssm spooky toxin

CAT: 0931-T80528-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80528-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) channels. It demonstrates IC50 values of 2.8 μM for Kv7.4, 5.26 μM for Kv1.3, and 0.1-0.3 M for the Shal channel, respectively. Additionally, this toxin impedes cytokine production by selectively targeting the KV1.3 channel in T cells and is crucial for the centipede's circulatory system functions [1] [2] [3].
Molecular Formula
C270H413N69O79S4
Molecular Weight
6017.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C