Products for Research Use Only
RegisterLogin

Ssm spooky toxin (TFA)

CAT: 0804-HY-P5925A-01Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P5925A-01Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ssm Spooky Toxin TFA is found in Scolopendra mutilans that potently inhibits KCNQ (voltage-gated potassium channel family 7) channels, with IC50s of 2.8 μM, 5.26 μM and 0.1-0.3 M for Kv7.4, Kv1.3, and Shal channel, respectivily. Ssm Spooky Toxin TFA inhibits cytokine generation by specifically acting on the KV1.3 channel in T cells. Ssm Spooky Toxin TFA plays an essential role in the centipede’s circulatory system[1] [2][3].
Product Name Alternative
SsTx Toxin (TFA)
UNSPSC
12352209
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Purity
99.09
Smiles
O=C([C@@H](N)CCC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N3[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H]4CCCCN)=O)CC5=CC=CC=C5)=O)CC6=CC=CC=C6)=O)=O)CCC3)=O)CCCCN)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CO)=O)CCC(O)=O)=O)CC(O)=O)=O)=O)=O)[C@@H](C)O)=O)CC7=CC=CC=C7)=O)CO)=O)[C@@H](C)O)=O)C)=O)CSSC[C@H](NC8=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC9=CC=CC=C9)=O)CC%10=CC=C(O)C=C%10)=O)=O)C)=O)CCCCN)=O)CC(C)C)=O)CSSC[C@H](NC4=O)C(N[C@H]8[C@@H](C)O)=O)=O)CCC(O)=O)=O)CO)=O)CCCCN)=O)CC%11=CC=C(O)C=C%11)=O)CCC2)=O)CC%12=CC=CC=C%12)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CC%13=CC=C(O)C=C%13)=O)CCC1)=O)[C@@H](C)O)=O)CC(O)=O)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C.O=C(O)C(F)(F)F.[x]
Molecular Formula
C270H413N69O79S4.xC2HF3O2
Molecular Weight
6017.84 (free base)
References & Citations
[1]Canwei Du, et al. Centipede KCNQ Inhibitor SsTx Also Targets KV1.3. Toxins (Basel) . 2019 Feb; 11 (2) : 76.|[2]Shilong Yang, et al. Target switch of centipede toxins for antagonistic switch. Sci Adv. 2020 Aug 7;6 (32) :eabb5734.|[3]Anna Luo, et al. Centipede Venom: A Potential Source of Ion Channel Modulators. Int J Mol Sci.2022 Jun 26;23 (13) :7105.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P5925Ssm spooky toxin
HY-P5807A-01Cn2 toxin (TFA)
HY-P5917A-01Vm24-toxin (TFA)
HY-P5914A-01Wasabi Receptor Toxin (TFA)
HY-P1754A-01Tetanus toxin (830-843) (TFA)
HY-P5425A-01Tetanus Toxin (830–844) (TFA)
HY-P5380ATNO211 (TFA)
HY-P4668A-01Valylleucine (TFA)
HY-P11296A-01LLVK (TFA)
HY-P10927A-01BRP (TFA)

Alternative Products

CatalogName
TN10752-01Ssm spooky toxin TFA
T80528-01Ssm spooky toxin
GTR19150513-01ShK toxin TFA
GTR19145224-01Vm24-toxin TFA
GTR19066031-01Wasabi Receptor Toxin TFA
TP3136-01Tetanus Toxin (830–844) TFA
GTR19144789-01Tetanus toxin (830-843) TFA
A8967-1EZM0414 TFA
C8651-10Pentosidine TFA
A8958-100Box5 TFA

Popular Products