ShK toxin

CAT: 0931-T80066-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T80066-01Size:5 mg
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CAS Number
172450-46-3
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel) . It competes with dendrotoxin I and ?-dendrotoxin in binding to rat brain synaptosomal membranes and promotes acetylcholine release. Additionally, ShK toxin reduces K+ currents in cultured rat dorsal root ganglion neurons and inhibits T lymphocyte proliferation [1] [2].
Molecular Formula
C169H274N54O48S7
Molecular Weight
4054.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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