ShK toxin

• Target:

  Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel) . It competes with dendrotoxin I and ?-dendrotoxin in binding to rat brain synaptosomal membranes and promotes acetylcholine release. Additionally, ShK toxin reduces K+ currents in cultured rat dorsal root ganglion neurons and inhibits T lymphocyte proliferation [1] [2].

• Molecular Formula:

  C169H274N54O48S7

• Molecular Weight:

  4054.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  172450-46-3