Products for Research Use Only

Cbl-b-IN-13

CAT: 0013-GTR19230156-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230156-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-13 is a potent small molecule inhibitor of the E3 ubiquitin ligase Cbl-b, demonstrating an IC50 below 100 nM. Its inhibition of Cbl-b leads to T-cell activation, making it a valuable research tool for studying immune-oncology and T-cell function in both cellular and animal models.
CAS Number
2368841-85-2
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
O=C1C2=CC (=CC (=C2CN1C3=CC=CC (=C3) C4 (COC4) CC5=NN=CN5C) C (F) (F) F) CN6CCC7 (C6) CC7
Molecular Formula
C29H30F3N5O2
Molecular Weight
537.58
Storage Conditions
-20°C
Notes
For research use only.