Cbl-b-IN-8

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  Cbl-b-IN-8 (Compound 293) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].

• Smiles :

  C(C1(COC1)C=2C=C(N=C(OC3CCCC3)C2)N4CC=5C(C4=O)=CC(CN6[C@@H]([C@H](C)C)CN(C)CC6)=CC5C(F)(F)F)C=7N(C)C=NN7

• Molecular Formula :

  C35H44F3N7O3

• Molecular Weight :

  667.76

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2815223-33-5