Products for Research Use Only

Cbl-b-IN-7

CAT: 0013-GTR19230163-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230163-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-7 (Compound 248) is a potent dual inhibitor of Cbl-b and c-Cbl with IC50 values of 6.7 nM and 5.2 nM, respectively. This small molecule is a valuable research tool for investigating E3 ubiquitin ligase function in immune cell signaling and has been utilized in both in vitro and in vivo studies of autoimmunity and cancer.
CAS Number
2815221-35-1
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
[C@@H] (F) (C1 (COC1) C2=CC (=CC=C2) N3CC=4C (C3=O) =CC ([C@@H] (NC5 (C) CCC5) C) =CC4C (F) (F) F) C=6N (C) C=NN6
Molecular Formula
C29H31F4N5O2
Molecular Weight
557.58
Storage Conditions
-20°C
Notes
For research use only.