GPX4-IN-7

• Target:

  Ferroptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 ?M. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1].

• Molecular Formula:

  C25H23ClN4O4

• Molecular Weight:

  478.93

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C