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GPX4-IN-7

CAT: 0931-T79777-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79777-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1].
Molecular Formula
C25H23ClN4O4
Molecular Weight
478.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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