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GPX4-IN-14

CAT: 0931-T200070-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200070-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis, Reactive Oxygen Species, Glutathione Peroxidase
Related Pathways
NF-κB, Apoptosis, Immunology/Inflammation, Metabolism
Bioactivity
GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.
Molecular Formula
C26H39NO8Se
Molecular Weight
572.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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