PDK-IN-2

CAT: 0931-T79723-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T79723-01Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Dehydrogenase|||Others|||Mitochondrial Metabolism
Related Pathways
Metabolism|||Others
Bioactivity
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells. It promotes mitochondrial bioenergetics, reduces glycolytic activity, and triggers apoptosis via the mitochondrial pathway. Additionally, PDK-IN-2 has been shown to impede tumor growth in a 4T1 syngeneic mouse model [1].
Molecular Formula
C17H23AsCl2N2O2S2
Molecular Weight
497.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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