PDK-IN-2

• Target:

  Dehydrogenase|||Others|||Mitochondrial Metabolism

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells. It promotes mitochondrial bioenergetics, reduces glycolytic activity, and triggers apoptosis via the mitochondrial pathway. Additionally, PDK-IN-2 has been shown to impede tumor growth in a 4T1 syngeneic mouse model [1].

• Molecular Formula:

  C17H23AsCl2N2O2S2

• Molecular Weight:

  497.33

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C