PDK-IN-1

• Target:

  Others|||Dehydrogenase|||HSP

• Related Pathways:

  Cytoskeletal Signaling|||Others|||Metabolism

• Bioactivity:

  PDK-IN-1 (compound 7o), a pyruvate dehydrogenase kinase (PDK) inhibitor, exhibits IC50 values of 0.03 and 0.1 ?M against PDK1 and HSP90, respectively. This compound effectively targets the PDH/PDK axis, significantly reducing tumor mass [1].

• Smiles:

  CN1C=C(C=2C1=NC=C(Br)C2)C=3C(=NN=C(N)N3)C=4C=5C(NC4)=CC=C(OC)C5

• Molecular Formula:

  C20H16BrN7O

• Molecular Weight:

  450.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2897696-10-3