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PDK-IN-1

CAT: 0931-T74830-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74830-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2897696-10-3
Target
Others, Dehydrogenase, HSP
Related Pathways
Cytoskeletal Signaling, Others, Metabolism
Bioactivity
PDK-IN-1 (compound 7o), a pyruvate dehydrogenase kinase (PDK) inhibitor, exhibits IC50 values of 0.03 and 0.1 μM against PDK1 and HSP90, respectively. This compound effectively targets the PDH/PDK axis, significantly reducing tumor mass [1].
Smiles
CN1C=C(C=2C1=NC=C(Br)C2)C=3C(=NN=C(N)N3)C=4C=5C(NC4)=CC=C(OC)C5
Molecular Formula
C20H16BrN7O
Molecular Weight
450.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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