PDK4-IN-2

• Target:

  Dehydrogenase

• Related Pathways:

  Metabolism

• Bioactivity:

  PDK4-IN-2 (compound 8), a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor, exhibits an inhibition concentration (IC 50) of 46 µM. By regulating bioenergetics and activating the tricarboxylic acid cycle [1], it enhances the ejection fraction in failing hearts.

• Smiles:

  O=C1C=2C(=C(O)C=C(C(OC)=O)C2)C(=O)C=C1C

• Molecular Formula:

  C13H10O5

• Molecular Weight:

  246.22

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1616752-12-5