PDK4-IN-2

CAT: 0931-T87124-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87124-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1616752-12-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
PDK4-IN-2 (compound 8), a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor, exhibits an inhibition concentration (IC 50) of 46 µM. By regulating bioenergetics and activating the tricarboxylic acid cycle [1], it enhances the ejection fraction in failing hearts.
Smiles
O=C1C=2C(=C(O)C=C(C(OC)=O)C2)C(=O)C=C1C
Molecular Formula
C13H10O5
Molecular Weight
246.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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