Products for Research Use Only

EGFR-IN-83

CAT: 0931-T79651-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79651-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR, Apoptosis
Related Pathways
Apoptosis, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-83 (Compound 9), an EGFR inhibitor with an IC50 of 2.53 nM, exhibits antiproliferative effects on MCF-7 and MDA-MB-231 cell lines, with respective IC50 values of 2.50 μM and 1.96 μM. Furthermore, EGFR-IN-83 is capable of inducing cell apoptosis [1].
Molecular Formula
C22H17F3N4O
Molecular Weight
410.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C