A 83-01

• Target:

  ALK|||TGF-beta/Smad

• Related Pathways:

  Angiogenesis|||Stem Cells|||Tyrosine Kinase/Adaptors

• Purity:

  0.9876

• Bioactivity:

  A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-? type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM) . A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.

• Smiles:

  Cc1cccc(n1)-c1nn(cc1-c1ccnc2ccccc12)C(=S)Nc1ccccc1

• Molecular Formula:

  C25H19N5S

• Molecular Weight:

  421.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  909910-43-6