BuChE-IN-9

• Target:

  Others|||GABA Receptor|||Beta-Secretase|||Cholinesterase (ChE)

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel|||Others

• Bioactivity:

  BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM. In addition to eqBuChE, it also inhibits human BACE1, A? aggregation, and mouse GABA transporters 1 and 4 (mGAT1 and mGAT4) . Notably, BuChE-IN-9 demonstrates significant antiamnesic properties [1].

• Molecular Formula:

  C28H34N4O2

• Molecular Weight:

  458.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C