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ARD-2051

CAT: 0931-T78922-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78922-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2632305-17-8
Target
Androgen Receptor, PROTACs
Related Pathways
PROTAC, Endocrinology/Hormones
Bioactivity
ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR protein within LNCaP and VCaP prostate cancer cell lines. It holds potential for prostate cancer research applications [1].
Smiles
C[C@H]1CC2(CN1C3=CC(Cl)=C(C#N)C=C3)CCN(CC2)C4=CC=C(C(=O)N5CCN(CC5)C6CN(C6)C=7C=C8C(=CC7)C(=O)N(C8=O)C9C(=O)NC(=O)CC9)C=C4
Molecular Formula
C43H45ClN8O5
Molecular Weight
789.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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