ARD-2051

• Target:

  Androgen Receptor|||PROTACs

• Related Pathways:

  PROTAC|||Endocrinology/Hormones

• Bioactivity:

  ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR protein within LNCaP and VCaP prostate cancer cell lines. It holds potential for prostate cancer research applications [1].

• Smiles:

  C[C@H]1CC2 (CN1C3=CC (Cl) =C (C#N) C=C3) CCN (CC2) C4=CC=C (C (=O) N5CCN (CC5) C6CN (C6) C=7C=C8C (=CC7) C (=O) N (C8=O) C9C (=O) NC (=O) CC9) C=C4

• Molecular Formula:

  C43H45ClN8O5

• Molecular Weight:

  789.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2632305-17-8