ARD-1676

CAT: 0931-MF-0063147-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0063147-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2632305-36-1
Target
PROTACs|||Androgen Receptor
Related Pathways
PROTAC|||Endocrinology/Hormones
Bioactivity
ARD-1676 is an orally administered androgen receptor (AR) PROTAC degrader that combines an AR ligand with a cereblon ligand. It demonstrates AR-degrading activity both in vitro and in vivo, and effectively inhibits VCaP tumor growth in mouse xenograft models [1].
Smiles
C[C@H]1CC2(CN1C3=CC(Cl)=C(C#N)C=C3)CCN(CC2)C4=CC=C(C(=O)N5CCC(CN6CC=7C(C6)=CC8=C(C7)C(=O)N(C8=O)C9C(=O)NC(=O)CC9)CC5)C=C4
Molecular Formula
C44H46ClN7O5
Molecular Weight
788.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5821386ARD-1676
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