LASSBio-2052

CAT: 0931-T86800-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T86800-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2549160-15-6
Target
Others|||Apoptosis|||DNA/RNA Synthesis
Related Pathways
Others|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Apoptosis
Bioactivity
LASSBio-2052, a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC), inhibits HCC cells HepG2 and Hep3B with IC50 values of 18 and 41 ?M, respectively. LASSBio-2052 arrests the cell cycle at G2/M phase through downregulation of FOXM1 and induces apoptosis in HCC cells [1].
Smiles
C(NN=CC1=CC=C(C(F)(F)F)C=C1)(=O)C2=C(NCC3=CC(O)=C(OC)C=C3)C=CC=C2
Molecular Formula
C23H20F3N3O3
Molecular Weight
443.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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